Research Overview —
I investigate how exercise can modulate brain health in the aspect of mitochondrial quality control in Alzheimer's disease. My study also aims to explore how the nutritional state influences the effectiveness of exercise and how different exercise modalities, like resistance and aerobic training, can potentially alleviate symptoms or delay the progression of Alzheimer's disease.
Publications —
Kugler BA, Lysaker CR, Franczak E, Hauger BM, Csikos V, Stopperan JA, Allen JA, Stanford JA, Koch LG, Britton SL, Thyfault JP, Wilkins HM. (2024) Intrinsic aerobic capacity modulates Alzheimer's disease pathological hallmarks, brain mitochondrial function and proteome during aging. Geroscience. doi: 10.1007/s11357-024-01248-3. PMID: 38867031
Franczak, E., Maurer, A., Drummond, V.C. et al. (2023) Divergence in aerobic capacity and energy expenditure influence metabolic tissue mitochondrial protein synthesis rates in aged rats. GeroScience https://doi.org/10.1007/s11357-023-00985-1
Fiáth R, Hofer K. T, Csikós V, Horváth D, Nánási T, Tóth K, Pothof F, Böhler C, Asplund M, Ruther P, Ulbert I. (2018) Long-term recording performance and biocompatibility of chronically implanted cylindrically shaped,polymer-based neural interfaces. Biomedical Engineering / Biomedizinische Technik 63(3): 301-315
Presentations —
Vivien Csikos, Brittany Hauger, Taylor Strope, Colton Lysaker, Edziu Franczak, Colin McCoin PhD, John Thyfault PhD, Heather Wilkins PhD. (November 2024) Dual Impact: Exercise and Fasting to Boost Brain Mitochondrial Health. Integrative Physiology of Exercise Conference, State College, PA
Vivien Csikos Drummond, Edziu Franczak, Colton Lysaker, Xin Cao, Colin McCoin PhD, John P. Thyfault PhD, Heather M. Wilkins PhD. (August 2023) Optimizing brain mitochondrial adaptations: the role of nutritional state during exercise. Mitochondrial Physiology – From Organelle to Organism, Copenhagen, Denmark.
Kaitlin Flannagan, Julia A Stopperan, Brittany M Hauger, Benjamin R Troutwine , Colton R Lysaker, Taylor A Strope, Vivien Csikos Drummond, Caleb A Gilmore, Natalie A Swerdlow , Julia M Draper, Cynthia M Gouvion, Jay L Vivian, Mohammad Haeri, Russell H Swerdlow, Heather M Wilkins. (August 2023) Cell type and sex specific mitochondrial phenotypes in iPSC derived models of Alzheimer's disease. Frontiers in Molecular Neuroscience
Vivien Csikos Drummond, Colton Lysaker, Edziu Franczak, Xin Cao, Ben Kugler PhD, Brittany Hauger, Riley Kemna, Taylor Strope, Madi Rickabaugh, Colin McCoin PhD, Julie Allen, Heather M. Wilkins PhD, John P. Thyfault PhD. (April 2023) Preliminary results for the effects of exercise on brain health and cognition in older rats with intrinsically low vs. high aerobic capacity. Student Research Forum, Kansas City, KS
Vivien Csikos Drummond, Colton R. Lysaker, Taylor A. Strope, Julie Allen, Heather M. Wilkins, John P. Thyfault. (November 2022). Chloroquine: a chemical to block fasting-induced autophagy in the mouse brain. 4th annual Henry and Amelia Nasrallah Center for Neuroscience research symposium. St Louis, MO
Julia M. Draper, Vivien Drummond, Scott Weir, Jay L. Vivian. (May 2022) A screen for therapies for Vici Syndrome, a rare neurodegenerative disorder of autophagy. Children’s Mercy Research Institute Internal Research Day
Csikós V, Fiáth R, Hegyi B, Tóth K, Wittner L, Pothof F, Ruther P, Ulbert I. Performance evaluation of chronically implanted, cylindrically-shaped polymer-based neural implants. HunDoc - Hungarian Neuroscience Doctoral Conference. 2016)
Csikós V, Fiáth R, Hegyi B, Tóth K, Wittner L, Pothof F, Ruther P, Ulbert I. Performance evaluation of chronically implanted, cylindrically-shaped polymer-based neural implants. IBRO - International Brain Research Organization, 2016
Awards and Honors —
- Selected for a T32 training grant funded by the National Institutes of Health, National Institute of Child Health and Human Development: Kansas Training Program in Neurological and Rehabilitation Sciences (2022-current)
- Best undergraduate Individual Laboratory thesis work and presentation (2017)