I started my research program on the role of lipid rafts as compartments for signaling via neurotrophin receptors. As changes in neurotrophin signaling are known to contribute to nerve degeneration in diabetic neuropathy, we extended our work to diabetic animal and cell culture models, which is the current thrust in the lab.
The specific aims of my research are designed to determine how the Msr system affects the function and expression of other proteins as well as to evaluate the role of methionine oxidation in the progression of oxidative stress and age related diseases.
Dr. Subramanian received his PhD in Molecular Biology from the University of Southern California. He completed a Postdoctoral Fellowship at the National Institutes of Health and a position as a Research Scientist at the Massachusetts Institute of Technology. During his postdoctoral research, he used in vitro and in vivo imaging technologies to understand mechanisms of synaptic plasticity in mouse cortical neurons.
Dr. Subramanian’s research focuses primarily on synaptic plasticity associated with learning and memory and their dysfunction in mouse models of neurodegenerative disorders. His lab utilizes state of the art approaches, such as single neuron genetic manipulations, in vivo synaptic labeling and multi-color two photon imaging.
Courtesy and Adjunct Professors
- Abdulbaki Agbas, Ph.D. - Adjunct Professor - Dept. of Biochemistry, Kansas City University of Medicine and Biosciences
- Ken Audus, Ph.D. - Courtesy Professor - School of Pharmacy
- Marco Bortolato, Ph.D. - Adjunct Associate Professor - College of Pharmacy, University of Utah
- Alexander Moise, Ph.D. - Adjunct Associate Professor - Northern Ontario School of Medicine